Journal: Cardiology Journal

Article Title: Feasibility of zero or near zero fluoroscopy during catheter ablation procedures

doi: 10.5603/CJ.a2018.0029

Figure Lengend Snippet: Left panel showing the three-dimensional electroanatomical CARTO maps (Biosense Webster, Diamond Bar, CA, USA) of right (gray) and left (green) atria with coronary sinus (blue) and right panel with three-dimensional reconstruction from magnetic resonance imaging. Both panels show the images from the anteroposterior view.

Article Snippet: All procedures were performed under conscious sedation using midazolam and fentanyl. fig ft0 fig mode=article f1 fig/graphic|fig/alternatives/graphic mode="anchored" m1 Open in a separate window Figure 1 caption a7 Left panel showing the three-dimensional electroanatomical CARTO maps (Biosense Webster, Diamond Bar, CA, USA) of right (gray) and left (green) atria with coronary sinus (blue) and right panel with three-dimensional reconstruction from magnetic resonance imaging.

Techniques: Magnetic Resonance Imaging

Journal: European Heart Journal

Article Title: Biological substrate modification suppresses ventricular arrhythmias in a porcine model of chronic ischaemic cardiomyopathy

doi: 10.1093/eurheartj/ehac042

Figure Lengend Snippet: Experimental protocol and delivery technique. (A) Myocardial infarction was induced by 90 min balloon occlusion of the proximal anterior descending branch of the left coronary artery followed by 8 weeks of reperfusion. Cardiac function and scar size were examined by magnetic resonance imaging. Arrhythmia inducibility was probed by programmed electrical stimulation at the left ventricular scar border. If no sustained arrhythmia was induced, programmed electrical stimulation was repeated at the right ventricular apex. High-density three-dimensional electroanatomic mapping was then performed (Rhythmia®, Boston Scientific). Inducible animals were randomly assigned to receive focal injections of either 7.5 mg of CDCEXO in 2 mL of IMDM or 2 mL of IMDM alone. Injections were performed in areas where late potentials were identified using electroanatomical mapping and confirmed by point-by-point mapping (NOGA®, Biosense Webster). Magnetic resonance imaging, electroanatomical mapping, and programmed electrical stimulation were repeated 2 weeks later. Animals were then euthanized, and the heart was removed for histologic and proteomic analysis. (B: Left) High-definition electroanatomical mapping image of the arrhythmogenic substrate with an identified late potential. (Centre) Schematic representation of delivery technique using intracardiac injection catheter (Myostar®, Biosense Webster). (Right) Representative NOGA® map with injection sites (black dots). (C) Animals injected with vehicle alone showed diminished contractile function (CDCEXO 3.11 ± 3.75% vs. control −4.7 ± 4.04%, P = 0.0006). (D) Cardiac output increased in CDCEXO pigs (CDCEXO 278.1 ± 414 mL/min vs. control −586 ± 605 mL/min, P = 0.0027). (E) Deleterious changes in end-systolic volumes (CDCEXO −1.4 ± 3.3 mL vs. control 8 ± 8.2 mL, P = 0.005) were observed in control but not in CDCEXO pigs. A two-tailed t-test was used to compare the changes between groups.

Article Snippet: High-density three-dimensional electroanatomic mapping was then performed (Rhythmia ® , Boston Scientific).

Techniques: Magnetic Resonance Imaging, Injection, Control, Two Tailed Test